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bivia, Mobiluncus mulieris , and Sneathia , among others often forming a dense polymicrobial biofilm 13,14,15,16,17

S.PimentelE.El-HageN.et al (2015)

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In contrast, inflammation arises from persistent accumulation of senescent cells, mitochondrial dysfunction (e.g., excessive mtROS), and immunometabolic dysregulation, characterized by chronic, low-level secretion of pro-inflammatory factors (e.g., IL-6, TGF-) 41

Gut microbiota dysfunction as reliable non-invasive early diagnostic biomarkers in the pathophysiology of Parkinsons disease: A critical review